Major depression and health-related quality of life in Parkinson’s disease
Authors: C. Allyson Jones, Sheri L. Pohar, and Scott B. Patten
Overview
Abstract (English)
Objective To evaluate the impact of depression and life stress on HRQL in the Canadian community dwelling population with PD. Methods A total of 259 respondents from the Canadian Community Health Survey (CCHS 1.1) with self-reported PD were interviewed. Measures included Health Utilities Index Mark 3 (HUI3), Composite International Diagnostic Interview Short Form for Major Depression and a single question regarding the amount of stress in their lives most days. Adjusted HUI3 scores were compared according to depression and life stress using ANCOVA models. Results Respondents without depression had overall HUI3 scores that were 0.29 units higher than respondents with depression [adjusted mean (95% CI) 0.49 (0.39-0.59) vs. 0.20 (0.03-0.37)]. The difference in overall HUI3 scores between respondents who reported high levels of stress as those who did not was 0.19 [adjusted mean (95% CI) 0.42 (0.29-0.55) vs. 0.23 (0.10-0.36)]. Conclusions Substantial impact of depression and life stress, two modifiable factors, on HRQL is seen in PD. HRQL may be improved by clinical management of these nonmotor symptoms in PD.
Abstract (French)
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Details
Type | Journal article |
---|---|
Author | C. Allyson Jones, Sheri L. Pohar, and Scott B. Patten |
Publication Year | 2009 |
Title | Major depression and health-related quality of life in Parkinson’s disease |
Volume | 3 |
Journal Name | General Hospital Psychiatry |
Number | 1 |
Pages | 334-340 |
Publication Language | English |
- C. Allyson Jones
- C. Allyson Jones, Sheri L. Pohar, and Scott B. Patten
- Major depression and health-related quality of life in Parkinson’s disease
- General Hospital Psychiatry
- 3
- 2009
- 1
- 334-340