Prevalence of cardiovascular risk factors and disease in people with schizophrenia: a population-based study
Authors: Lauren C. Bresee, Sumit R. Majumdar, Scott B. Patten, and Jeffrey A. Johnson
Objective To evaluate the prevalence of cardiovascular risk factors (CV-RF) and disease (CV-D) in people with schizophrenia. Method We conducted a period-prevalence study using a population-based cohort from Alberta administrative databases. Schizophrenia was identified using billing codes; all other individuals served as non-schizophrenic controls. Modifiable CV-RF (hypertension, dyslipidemia, diabetes) and established CV-D (acute coronary syndrome (ACS), chronic ischemic heart disease (IHD), heart failure (HF), stroke, arrhythmia) were identified using previously validated methods. Analyses were conducted using multivariable logistic regression. Results From 1995 to 2006, 28,755 people (1.2%) were identified with schizophrenia and compared with 2,281,636 non-schizophrenic controls. Individuals with schizophrenia were older (mean age 47.6years vs. 45.3) and had lower socioeconomic status (59% received healthcare subsidies vs. 21%; OR: 5.55; 95% CI: 5.42-5.69) than controls. Of the CV-RF, diabetes was more common in those with schizophrenia than controls, particularly in younger males (ages 30-39, 3.8% vs. 1.4%, aOR: 1.57; 95% CI: 1.30-1.91) and females (ages 30-39, 5.8% vs. 2.4%, aOR: 1.72; 95% CI: 1.44-2.04). The prevalence of CV-D was significantly higher in people with schizophrenia than controls (27% vs. 17%, OR: 1.76; 95% CI: 1.72-1.81). Conclusions On a population-wide basis, people with schizophrenia had a higher prevalence of diabetes and cardiovascular disease than those without schizophrenia, particularly at a younger age. Female sex offered no cardiovascular protection in those with schizophrenia. Our data suggest monitoring for diabetes and other cardiovascular risk factors should begin at the time of diagnosis of schizophrenia, particularly in females with schizophrenia.
Please note that abstracts only appear in the language of the publication and might not have a translation.
Lauren C. Bresee, Sumit R. Majumdar, Scott B. Patten, and Jeffrey A. Johnson (2010).
Diabetes, cardiovascular disease, and health care use in people with and without schizophrenia
Maude Boulet (2012).
Le degré de déqualification professionnelle et son effet sur les revenus des femmes immigrantes membres d'une minorité visible du Québec
Revue Femmes et Droit / Canadian Journal of Women and the Law , 53-81
Douglas Almond, Lena Edlund, and Kevin Milligan (2013).
Son preference and the persistence of culture: Evidence from South and East Asian immigrants to Canada
Population and Development Review , 75-95
Stella Park (2012).
Filipino youth in Canada: Demographic, residential, economic, educational and occupational profile of filipino youth in Canada using 2006 Census
E.-Martin Meunier, Sarah Wilkins-Laflamme, and Véronique Grenier (2013).
La langue gardienne de la religion / La religion gardienne de la langue? Note sur la permanence et recomposition du catholicisme au Québec et dans la francophonie canadienne
Francophonies d'Amérique , 13-40