Depression and painful conditions: Patterns of association with health status and health utility ratings in the general population
Authors: Scott B. Patten, Jeanne V. A. Williams, Dina H. Lavorato, Andrew G. M. Bulloch, Gillian Currie, and Herb Emery
Purpose: Preference-weighted HRQoL (utility) ratings are increasingly used to guide clinical and resource allocation decisions, but their performance has not always been adequately explored. We sought to examine patterns of health utility ratings in community populations with depressive disorders and painful conditions. Methods: We used two Canadian cross-sectional health surveys that obtained Comprehensive Health Status Measurement System/Health Utilities Index Mark 3 (HUI3) ratings and identified people with painful conditions and major depression. We estimated the frequency of item endorsements and mean utility ratings in these groups. Results: Interesting differences between health state ratings and diagnostic categories were noted. For example, 71 % of those professionally diagnosed with migraine reported that they usually have “no pain.” Despite this, utility ratings were lower in those respondents with depressive episodes and in those with painful conditions. Greater than additive reductions in HUI3 scores were noted in most instances where both depressive disorders and painful conditions were present. Conclusions: Health utility ratings confirm the clinical impression that painful conditions and depressive disorders magnify each other’s impact. Despite weak alignment between the health state definitions incorporated into utility ratings and the diagnostic concepts examined, the HUI3 appeared to capture HRQoL decrements and negative synergies associated with the co-occurrence of depressive episodes and painful conditions.
Please note that abstracts only appear in the language of the publication and might not have a translation.
|Author||Scott B. Patten, Jeanne V. A. Williams, Dina H. Lavorato, Andrew G. M. Bulloch, Gillian Currie, and Herb Emery|
|Title||Depression and painful conditions: Patterns of association with health status and health utility ratings in the general population|
|Journal Name||Quality of Life Research|
- Scott B. Patten
- Scott B. Patten, Jeanne V. A. Williams, Dina H. Lavorato, Andrew G. M. Bulloch, Gillian Currie, and Herb Emery
- Depression and painful conditions: Patterns of association with health status and health utility ratings in the general population
- Quality of Life Research
S. L. Maddigan, D. Feeny, and J. Johnson (2005).
Health-related quality of life deficits associated with diabetes and comorbidities in a Canadian National Population Survey
Quality of Life Research , 1311-1320
Katya M. Herman, Wilma M. Hopman, and Mark W. Rosenberg (2013).
Self-rated health and life satisfaction among Canadian adults: Associations of perceived weight status versus BMI
Quality of Life Research , 2693-2705
Richard Sawatzky, Pamela A. Ratner, Jacek A. Kopec, and Bruno D. Zumbo (2012).
Latent variable mixture models: A promising approach for the validation of patient reported outcomes
Quality of Life Research , 637-650
Lauren Hirsch, Scott B. Patten, Lauren Bresee, Nathalie Jette, and Tamara Pringsheim (2018).
Second-generation antipsychotics and metabolic side-effects: Canadian population-based study
BJPsych Open , 256-261
Ian Colman, Yiye Zeng, Anushka Ataullahjan, Ambikaipakan Senthilselvan, and Scott B. Patten (2011).
The association between antidepressant use and depression eight years later: a national cohort study
Journal of Psychiatric Research , 1012-1018
Scott B. Patten, Jeanne V. A. Williams, Dina H. Lavorato, Kirsten M. Fiest, Andrew G. M. Bulloch, and JianLi Wang (2015).
The prevalence of major depression is not changing
Canadian Journal of Psychiatry , 31-34
Scott B. Patten, Jeanne V. A. Williams, Dina H. Lavorato, Benjamin Woolf, Jian L. Wang, Andrew G. M. Bulloch, and Tolulope T. Sajobi (2018).
Major depression and second hand smoke exposure
Journal of Affective Disorders , 260-264