Probabilistic risk assessment for milk in dark chocolate, cookies and other baked goods with PAL sold in Canada
Auteurs: Emilie Manny, Sébastien La Vieille, Silvia A. Dominguez, Gregor Kos, Virginie Barrère, Jérémie Théolier, Joseph Touma, et Samuel Benrejeb Godefroy
Aperçu
Résumé (français)
Veuillez noter que les résumés n'apparaissent que dans la langue de la publication et peuvent ne pas avoir de traduction.
Résumé (anglais)
Highlights * Dark chocolate has a higher risk of milk allergen intake than cookies/baked goods. * Avoidance of dark chocolate with precautionary labeling by milk-allergic consumers is suggested. * Eliciting doses (ED) calculated were in close agreement with ED published by other authors. * Average exposure levels for all foods were superior to the calculated and published ED01. * Risk assessments should be based on up-to-date national consumption data instead of serving sizes. Abstract The risk of having an allergic reaction in milk-allergic individuals consuming products with precautionary allergen labelling (PAL) for milk has been rarely studied in products such as dark chocolate, cookies, and other baked goods. A probabilistic risk assessment model was developed to estimate potential risks. Milk occurrence and contamination levels were reported in a previous article from our group. Dose-response curves for milk were constructed using values (n = 1078) from published double-blind placebo-controlled food challenges. Canadian consumption data was extracted from a national survey, and a homemade survey involving food-allergic Canadians. Milk eliciting doses (ED) were 0.23 (ED01), 1.34 (ED05), 3.42 (ED10), and 16.3 (ED25) mg of milk protein (Log-Normal distribution). Average exposures, per eating occasion, were 24 mg (dark chocolate), 3.9 mg (baked goods), and 0.20 mg (cookies) of milk proteins. The estimated risk of having a milk-induced allergic reaction by consuming foods with PAL for milk was higher for dark chocolate (16%; 15,881/100,000) than baked goods (3.8%; 3802/100,000) or cookies (0.6%; 646/100,000) in milk-allergic Canadians. Dark chocolate, cookies, and baked goods with PAL for milk, should be avoided by milk-allergic Canadians (consuming or not products with PAL) to prevent allergic reactions.
Détails
Type | Article de journal |
---|---|
Auteur | Emilie Manny, Sébastien La Vieille, Silvia A. Dominguez, Gregor Kos, Virginie Barrère, Jérémie Théolier, Joseph Touma, et Samuel Benrejeb Godefroy |
Année de pulication | 2021 |
Titre | Probabilistic risk assessment for milk in dark chocolate, cookies and other baked goods with PAL sold in Canada |
Volume | 152 |
Nom du Journal | Food and Chemical Toxicology |
Numéro | June |
Langue de publication | Anglais |
- Emilie Manny
- Emilie Manny, Sébastien La Vieille, Silvia A. Dominguez, Gregor Kos, Virginie Barrère, Jérémie Théolier, Joseph Touma, et Samuel Benrejeb Godefroy
- Probabilistic risk assessment for milk in dark chocolate, cookies and other baked goods with PAL sold in Canada
- Food and Chemical Toxicology
- 152
- 2021
- June